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<p>The intensity of accumulation and excretion of atrial natriuretic peptide (ANP) in right atrial myocytes of 1-day-old offspring born to female rats with streptozotocin-induced type 1 diabetes mellitus was studied using transmission electron microscopy and immunocytochemistry. The data indicate a reduced ANP content relative to the control group. No significant differences were found in the morphometric characteristics of the right atrium ultrastructure between the control and experimental groups.</p>

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Content of Atrial Natriuretic Peptide in Cardiomyocytes Granules of Newborn Female Rats with Type 1 Diabetes Mellitus

  • 期刊论文

  • 发表日期：

    2026年1月1日

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  • D. A. Nefedova,
  • M. L. Bugrova,
  • G. V. Bryukhin

摘要

The intensity of accumulation and excretion of atrial natriuretic peptide (ANP) in right atrial myocytes of 1-day-old offspring born to female rats with streptozotocin-induced type 1 diabetes mellitus was studied using transmission electron microscopy and immunocytochemistry. The data indicate a reduced ANP content relative to the control group. No significant differences were found in the morphometric characteristics of the right atrium ultrastructure between the control and experimental groups.