Scholarlink

<p>We studied the effects of ACTH<sub>6-9</sub>-Pro-Gly-Pro on the morphofunctional state of the colon wall under conditions of prolonged stress. It was found that N-terminal analogue of ACTH, ACTH<sub>6-9</sub>-Pro-Gly-Pro mitigated morphofunctional disorders in the colon wall caused by 28-day restraint stress and accelerated adaptation by reducing the number of inflammatory infiltrate cells and mast cells. The most pronounced changes were observed after treatment with the peptide at a dose of 500 μg/kg.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effects of ACTH6-9-Pro-Gly-Pro Peptide on the Morphofunctional State of the Colon Wall under Conditions of Prolonged Stress

  • 期刊论文

  • 发表日期：

    2025年12月1日

查看全文
  • Ya. I. Bobyntsev,
  • E. V. Gavriliuk,
  • A. O. Vorvul,
  • I. I. Bobyntsev,
  • E. S. Mishina

摘要

We studied the effects of ACTH6-9-Pro-Gly-Pro on the morphofunctional state of the colon wall under conditions of prolonged stress. It was found that N-terminal analogue of ACTH, ACTH6-9-Pro-Gly-Pro mitigated morphofunctional disorders in the colon wall caused by 28-day restraint stress and accelerated adaptation by reducing the number of inflammatory infiltrate cells and mast cells. The most pronounced changes were observed after treatment with the peptide at a dose of 500 μg/kg.