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<p>Coagulation hemostasis parameters were assessed in non-human primates of the genus <i>Macaca</i> spp. specifically <i>Macaca mulatta</i> and <i>Macaca fascicularis</i> (age 1-34 years) housed in open enclosures at the Kurchatov Complex of Medical Primatology, National Research Centre “Kurchatov Institute” under humid subtropical climatic conditions. A high degree of interspecific variability in the measured hemostatic parameters was observed among sexually mature individuals of both species. Statistically significant differences were found in the mean values of coagulation parameters between immature and mature animals. Furthermore, in the age group of 20 years and older (classified as aged animals), significant sex-dependent differences in the mean values of the studied hemostasis indicators were also detected. The quantitative reference ranges obtained in this study can serve as a baseline for interpreting hemostasiological data in laboratory studies involving these primate species.</p>

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Coagulation Hemostasis Parameters in Macaque Monkeys (Macaca spp.)

  • 期刊论文

  • 发表日期：

    2025年11月1日

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  • O. A. Shamsutdinova,
  • A. P. Zlobina,
  • V. V. Keburiya,
  • M. A. Kotova,
  • A. P. Trashkov

摘要

Coagulation hemostasis parameters were assessed in non-human primates of the genus Macaca spp. specifically Macaca mulatta and Macaca fascicularis (age 1-34 years) housed in open enclosures at the Kurchatov Complex of Medical Primatology, National Research Centre “Kurchatov Institute” under humid subtropical climatic conditions. A high degree of interspecific variability in the measured hemostatic parameters was observed among sexually mature individuals of both species. Statistically significant differences were found in the mean values of coagulation parameters between immature and mature animals. Furthermore, in the age group of 20 years and older (classified as aged animals), significant sex-dependent differences in the mean values of the studied hemostasis indicators were also detected. The quantitative reference ranges obtained in this study can serve as a baseline for interpreting hemostasiological data in laboratory studies involving these primate species.