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<p>In rats subjected to increasing restriction of motor activity starting from day 21 days of life, copper content was evaluated by electron paramagnetic resonance (EPR) spectroscopy by analyzing the levels of copper-containing paramagnetic complexes in the heart and liver tissues. Copper content was assessed by the intensity of the characteristic EPR signal from the Cu<sup>2+</sup>-diethyldithiocarbamate complex (Cu<sup>2+</sup>-(DETC)<sub>2</sub>). It was found that after restriction of motor activity for 30 days, copper content in the heart and liver tissues increased by 2.2 and 2.9 times, respectively.</p>

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Effect of Motor Activity Restriction on Copper Content in Rats

  • 期刊论文

  • 发表日期：

    2025年1月1日

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  • R. I. Zaripova,
  • G. G. Yafarova,
  • V. V. Andrianov,
  • M. I. Sungatullina,
  • N. I. Ziyatdinova,
  • Kh. L. Gainutdinov,
  • T. L. Zefirov

摘要

In rats subjected to increasing restriction of motor activity starting from day 21 days of life, copper content was evaluated by electron paramagnetic resonance (EPR) spectroscopy by analyzing the levels of copper-containing paramagnetic complexes in the heart and liver tissues. Copper content was assessed by the intensity of the characteristic EPR signal from the Cu2+-diethyldithiocarbamate complex (Cu2+-(DETC)2). It was found that after restriction of motor activity for 30 days, copper content in the heart and liver tissues increased by 2.2 and 2.9 times, respectively.