Association of the Genotype of TNFα with the Efficiency of the Intensive Phase of Chemotherapy and Formation of the Sizes of Destruction Cavities in Patients with Pulmonary Tuberculosis

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发表日期：

2024年11月22日

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N. P. Balobanova,
M. A. Alymenko,
R. Sh. Valiev,
N. R. Valiev,
Ya. A. Safonov,
V. A. Lipatov,
A. V. Polonikov,
V. A. Ragulina,
G. S. Mal,
V. M. Kolomiets

摘要

The interrelation between the TNFα gene polymorphism and the effectiveness of the intensive phase of chemotherapy in patients with pulmonary tuberculosis, as well as the formation of diameter of the sizes of destruction cavities was studied. It was revealed that the most adverse course of the disease and a high frequency of formation of destruction cavities are associated with the GG genotype of the TNFα gene.