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Morphofunctional State of the Ovaries in Rats with Experimental Model of Functional Cysts and Their Treatment with Gonadotropin-Releasing Hormone Antagonist

  • O. S. Timofeeva,
  • S. V. Logvinov,
  • I. A. Petrov,
  • O. A. Tikhonovskaya,
  • Yu. G. Samoilova,
  • Zh. F. Gaifulina,
  • L. R. Mustafina,
  • M. S. Petrova,
  • A. A. Zhdankina,
  • I. G. Kutsenko,
  • D. A. Kudlay,
  • K. A. Sidorenkova

摘要

The morphofunctional features of the ovaries were evaluated in rats with functional ovarian cysts model treated with gonadotropin-releasing hormone antagonist. Administration of the antagonist significantly (p=0.009) reduced the number of cysts and the growth of follicles in the ovaries. The obtained results attest to a possibility of successful treatment of functional ovarian cysts with gonadotropin-releasing hormone antagonist.