Scholarlink

<p><i>Enterocytozoon hepatopenaei</i> (EHP) is an obligate intracellular microsporidian parasite that has become a major constraint to shrimp aquaculture, particularly in <i>Penaeus vannamei</i>. Unlike pathogens associated with acute mortality, EHP causes hepatopancreatic microsporidiosis (HPM), leading to substantial production losses worldwide. This review synthesizes current understanding of EHP biology and infection strategies, emphasizing its highly specialized intracellular lifestyle and strong dependence on host cellular resources. Accumulating evidence indicates that EHP disrupts host metabolic homeostasis and physiological regulation, thereby impairing growth performance. We further summarize current approaches for EHP detection and discuss key environmental and biological factors that influence disease emergence and persistence in farming systems. Although effective treatments are not yet available, emerging concepts for disease mitigation and future research priorities are highlighted. Overall, this review integrates recent biological insights to clarify EHP pathogenesis and provides a conceptual basis for improved risk assessment and management of EHP in shrimp aquaculture.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Silent threat in shrimp aquaculture: understanding and controlling Enterocytozoon hepatopenaei

  • 期刊论文

  • 发表日期：

    2026年2月16日

查看全文
  • Linh T. T. Le,
  • Thuan Duc Lao,
  • Nguyen Hoai Nguyen,
  • Phuong-Uyen Le,
  • Hoang Anh Tran,
  • Thuy Huyen Ai Le,
  • Phuong Vy Nguyen

摘要

Enterocytozoon hepatopenaei (EHP) is an obligate intracellular microsporidian parasite that has become a major constraint to shrimp aquaculture, particularly in Penaeus vannamei. Unlike pathogens associated with acute mortality, EHP causes hepatopancreatic microsporidiosis (HPM), leading to substantial production losses worldwide. This review synthesizes current understanding of EHP biology and infection strategies, emphasizing its highly specialized intracellular lifestyle and strong dependence on host cellular resources. Accumulating evidence indicates that EHP disrupts host metabolic homeostasis and physiological regulation, thereby impairing growth performance. We further summarize current approaches for EHP detection and discuss key environmental and biological factors that influence disease emergence and persistence in farming systems. Although effective treatments are not yet available, emerging concepts for disease mitigation and future research priorities are highlighted. Overall, this review integrates recent biological insights to clarify EHP pathogenesis and provides a conceptual basis for improved risk assessment and management of EHP in shrimp aquaculture.

Graphical Abstract