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Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects

  • Denise Honeycutt,
  • Arno Schmidt-Trucksäss,
  • Marijke Brink,
  • Nicolle Kränkel,
  • Julia M. Kröpfl

摘要

This study explores how 14–15 h fasting or acute exercise affects immune cell epigenetics, specifically focusing on miRNAs in mononuclear cells. Findings suggest fasting significantly impacts microRNAs associated with endothelial metabolism compared to exercise, but does not directly connect these changes to cell apoptosis or autophagy. This enhances comprehension of cellular self-consumption under health-promoting interventions.