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<p>Resonant nasal phonation is hypothesized to modulate autonomic function via vagal pathways, offering a potential non-pharmacological self-regulation strategy. A comprehensive efficacy synthesis and testable neuro-acoustic mechanism are lacking. This study introduces the Spirituo-Cardio-Neurology (S-CN) framework. To quantify the efficacy of phonation-based protocols on vagal tone (HRV-RMSSD, H2) and stress (cortisol, H3) and generate preliminary evidence for a mechanistic hypothesis (H1) linking acoustic properties to autonomic outcomes. A PRISMA 2020-compliant systematic review of 9248 records identified 123 studies. A random-effects meta-analysis of 23 high-quality trials (N = 1247) evaluated primary outcomes.&#xa0;A complementary computational linguistic analysis quantified nasal phoneme density using Quranic Tajwid recitation as a standardized, high-fidelity acoustic model<b>.</b>&#xa0;A meta-regression analysis controlled for respiratory parameters to isolate a unique phonetic effect. Meta-analysis confirmed that phonation-based protocols significantly enhance vagal tone (H2: RMSSD SMD = 0.92, 95% CI [0.65, 1.19],&#xa0;<i>p</i> &lt; 0.001) and reduce cortisol (H3: SMD = −&#xa0;0.54, 95% CI [−&#xa0;0.72, −&#xa0;0.36],&#xa0;<i>p</i> &lt; 0.001<i> p</i> &lt; 0.001). The computational analysis established the high nasal phoneme density of the model corpus. Crucially, the meta-regression yielded a conservative, adjusted estimate for the unique association between nasal phoneme exposure and vagal tone enhancement (β = 0.42, <i>p</i> &lt; 0.01), offering preliminary quantitative support for the proposed neuro-acoustic mechanism (H1) and grounding future biofeedback applications.</p>

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Phonation-Based Spiritual Practices and Autonomic Regulation: A Systematic Review and Meta-Analysis Testing the S-CN Model

  • 期刊论文

  • 发表日期：

    2026年3月18日

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  • Baghdad Kebdani

摘要

Resonant nasal phonation is hypothesized to modulate autonomic function via vagal pathways, offering a potential non-pharmacological self-regulation strategy. A comprehensive efficacy synthesis and testable neuro-acoustic mechanism are lacking. This study introduces the Spirituo-Cardio-Neurology (S-CN) framework. To quantify the efficacy of phonation-based protocols on vagal tone (HRV-RMSSD, H2) and stress (cortisol, H3) and generate preliminary evidence for a mechanistic hypothesis (H1) linking acoustic properties to autonomic outcomes. A PRISMA 2020-compliant systematic review of 9248 records identified 123 studies. A random-effects meta-analysis of 23 high-quality trials (N = 1247) evaluated primary outcomes. A complementary computational linguistic analysis quantified nasal phoneme density using Quranic Tajwid recitation as a standardized, high-fidelity acoustic model. A meta-regression analysis controlled for respiratory parameters to isolate a unique phonetic effect. Meta-analysis confirmed that phonation-based protocols significantly enhance vagal tone (H2: RMSSD SMD = 0.92, 95% CI [0.65, 1.19], p < 0.001) and reduce cortisol (H3: SMD = − 0.54, 95% CI [− 0.72, − 0.36], p < 0.001 p < 0.001). The computational analysis established the high nasal phoneme density of the model corpus. Crucially, the meta-regression yielded a conservative, adjusted estimate for the unique association between nasal phoneme exposure and vagal tone enhancement (β = 0.42, p < 0.01), offering preliminary quantitative support for the proposed neuro-acoustic mechanism (H1) and grounding future biofeedback applications.