Given separable Hilbert spaces \(\mathcal{H}\) , \(\mathcal{K}_1\) , and \(\mathcal{K}_2\) , we analyze Hilbert-Schmidt frames for \(\mathcal{H}\) with respect to the tensor product \(\mathcal{K}_1 \otimes \mathcal{K}_2\) . First, we give a characterization of Hilbert-Schmidt frames for \(\mathcal{H}\) with respect to \({\mathcal{K}_1 \otimes \mathcal{K}_2}\) . The construction of the Hilbert-Schmidt frames for \(\mathcal{H}\) with respect to \(\mathcal{K}_1 \otimes \mathcal{K}_2\) in terms of discrete frames for \(\mathcal{H}\) is presented. Sufficient conditions for the existence of Hilbert-Schmidt dual frames are given. We give the construction of Hilbert-Schmidt orthonormal bases, and sufficient conditions for the existence of Riesz bases for \(\mathcal{H}\) with respect to \(\mathcal{K}_1 \otimes \mathcal{K}_2\) .