This paper deals with the radial symmetry of positive solutions to the nonlocal problem \(( - \Delta )_\gamma ^su = b(x)f(u)\,\,\,\,\,{\rm{in}}\,\,\,{B_1}\backslash \{ 0\} ,\,\,\,\,\,\,u = h\,\,\,\,{\rm{in}}\,\,{\mathbb{R}^N}\backslash {B_1},\) where b: B1 → ℝ is locally Holder continuous, radially symmetric and decreasing in the ∣x∣ direction, f: ℝ → ℝ is a Lipschitz function, h: B1 → ℝ is radially symmetric, decreasing with respect to ∣x∣ in ℝNB1, B1 is the unit ball centered at the origin, and \(( - \Delta )_\gamma ^s\) is the weighted fractional Laplacian with s ∈ (0, 1), γ ∈ [0, 2s) defined by \(( - \Delta )_\gamma ^su(x) = {c_{N,s}}\mathop {\lim }\limits_{\delta \to {0^ + }} \int_{{\mathbb{R}^N}\backslash {B_\delta }(x)} {{{u(x) - u(y)} \over {|x - y{|^{N + 2s}}}}|y{|^\gamma }{\rm{d}}y.} \)
We consider the radial symmetry of isolated singular positive solutions to the nonlocal problem in whole space \(( - \Delta )_\gamma ^su(x) = b(x)f(u)\,\,\,\,\,{\rm{in}}\,\,{\mathbb{R}^N}\backslash \{ 0\} ,\) under suitable additional assumptions on b and f. Our symmetry results are derived by the method of moving planes, where the main difficulty comes from the weighted fractional Laplacian. Our results could be applied to get a sharp asymptotic for semilinear problems with the fractional Hardy operators \({( - \Delta )^s}u + {\mu \over {|x{|^{2s}}}}u = b(x)f(u)\,\,\,\,{\rm{in}}\,\,\,{B_1}\backslash \{ 0\} ,\,\,\,\,\,\,\,\,u = h\,\,\,\,\,\,{\rm{in}}\,\,\,{\mathbb{R}^N}\backslash {B_1},\) under suitable additional assumptions on b, f and h.