Active block EX-CCII based electrical circuit for practical impedance data of OSCC

Oral Squamous Cell Carcinoma (OSCC) is the most common oral cancer, and its behavior can be analyzed using bio-impedance. A single dispersion Cole model is designed using active block Extra X Current Conveyor (EX-CCII), which generates the existing practical oral OSCC bio-impedance data. An experimental result of cancer bio-impedance in the 20 Hz to 5 MHz range is well modeled with an active block EX-CCII resistors (R \(_{\infty }\) $_{\infty }^{}$ and R₁) and fractional capacitor (C_α). The proposed design can serve as a step forward for designing a purposeful method for analyzing the behavior of oral cancer impedance without any practical data. The functionality of the proposed electrical circuit for OSCC is well verified through PSPICE simulation using both 0.25 μm CMOS TSMC Technology parameters and the macro model of EX-CCII. Simulation results agree well with experimental bio-impedance data.