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<p>We assessed the relationship between same-day and next-day antiretroviral therapy (ART) adherence and adherence self-efficacy, daily routine disruptions, mental health, sleep, social support, substance use, and contextual factors in an ecological momentary assessment (EMA) study. Twenty-eight days of data from a convenience sample of 54 18-34-year-old young Latino sexual minority men (YLSMM) was used in generalized mixed models. Participants adhered to ARTs on 96% of 1,306 person-days. Daily motivation to stay healthy, to prevent HIV transmission, and ART self-efficacy were associated with same-day adherence. Routine disruptions, poor sleep, and drug use were associated with same-day non-adherence. Stress was associated with next-day non-adherence, and increased routine disruptions with non-adherence. Findings suggest an opportunity to design and test innovative interventions for YLSMM to improve ART adherence that increase daily adherence motivation and self-efficacy and provide real-time assistance during changes in routine, poor sleep, drug use, and stress.</p>

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Daily Factors Associated with Antiretroviral Therapy Adherence Among Young Latino Sexual Minority Men with HIV: A 28-Day Daily Diary Study

  • 期刊论文

  • 发表日期：

    2025年5月15日

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  • Diana M. Sheehan,
  • Daisy Ramírez-Ortiz,
  • Tendai Gwanzura,
  • Patrice S. Lewis,
  • Melissa M. Ertl,
  • Dustin T. Duncan,
  • Dallas Swendeman,
  • Miguel Muñoz-Laboy,
  • Jessy G. Devieux,
  • Mary Jo Trepka

摘要

We assessed the relationship between same-day and next-day antiretroviral therapy (ART) adherence and adherence self-efficacy, daily routine disruptions, mental health, sleep, social support, substance use, and contextual factors in an ecological momentary assessment (EMA) study. Twenty-eight days of data from a convenience sample of 54 18-34-year-old young Latino sexual minority men (YLSMM) was used in generalized mixed models. Participants adhered to ARTs on 96% of 1,306 person-days. Daily motivation to stay healthy, to prevent HIV transmission, and ART self-efficacy were associated with same-day adherence. Routine disruptions, poor sleep, and drug use were associated with same-day non-adherence. Stress was associated with next-day non-adherence, and increased routine disruptions with non-adherence. Findings suggest an opportunity to design and test innovative interventions for YLSMM to improve ART adherence that increase daily adherence motivation and self-efficacy and provide real-time assistance during changes in routine, poor sleep, drug use, and stress.