<p>We examine the relationship between mindfulness and eudaimonic well-being in Thai adults, a population largely overlooked in mindfulness research despite the strong influence of Buddhism within this culture. Specifically, we hypothesized that hope and meaning will account for variance in this relationship. Utilizing self-report measures for mindfulness, hope, meaning in life, and eudaimonic well-being, findings from a sample of 269 Thai adults revealed significant positive correlations between all of these constructs and eudaimonic well-being. Regression analyses also indicated that hope and meaning in life accounted for statistically significant variance in the relationship between mindfulness and eudaimonic well-being and that mindfulness, meaning, and hope collectively accounted for 63% of the variance in eudaimonic well-being. These results contribute to our cross-cultural understanding of variables related to well-being.</p>