Chronischer Husten: Symptom oder Krankheit?
摘要
In European countries the prevalence of chronic cough (lasting 8 or more weeks) is 4–10.9 %. Almost all pulmonary diseases can cause chronic cough, therefore making the appropriate diagnosis is essential. The basic diagnostic procedure comprises the history with characteristics of the cough, physical examination, chest X‑ray and a lung function test. Further “personalized” diagnostics are indicated if needed, according to the individual patientʼs complaints. Cough variant asthma (with normal spirometry), gastroesophageal reflux and upper airway diseases must be anticipated. Treatment with angiotensin-converting enzyme inhibitors should be switched to another treatment because it increases the sensitivity of the cough reflex, even in young healthy subjects. In 10–20 % of patients with chronic cough, the diagnosis is elusive and the cause of the cough cannot be determined. In these cases, a hypersensitive cough reflex elicits cough even to weak stimuli, called hypertussia or with unusual stimuli, not causing cough in healthy people, e.g., longer speaking, called allotussia. Thus, this cough is not a symptom of a distinct disease, it is a disease on its own, called refractory or unexplained chronic cough. Previously, the motto was: keep searching until a cause has been determined; however, in the case of refractory chronic cough, this conception leads to countless unnecessarily repeated diagnostic measures. In Germany, chronic refractory or unexplained cough can be coded with the International Classification of Diseases (ICD) 10 additional code 69.6 (apart from R05).