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Objective <p>Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a&#xa0;major driver of premature mortality in patients with rheumatoid arthritis (RA). Detection of RA-ILD is crucial but requires awareness among the treating physicians. To date, however, there is no international recommendation concerning screening for ILD in RA patients.</p> Methods <p>After a&#xa0;systematic literature review, the modified Delphi technique in combination with the nominal group technique was used to provide a&#xa0;Delphi consensus statement elaborated by an expert panel of pneumonologists, rheumatologists, and a&#xa0;radiologist. Based on the available evidence, several clusters of questions were defined and discussed until consent was reached.</p> Results <p>A&#xa0;screening algorithm for ILD in patients with RA based on clinical signs, respiratory symptoms, and risk factors has been developed. Further, the recommendations address diagnostic tools for RA-ILD and the follow-up of RA patients qualifying for ILD screening.</p>

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Screening for rheumatoid arthritis-associated interstitial lung disease—a Delphi-based consensus statement

  • 期刊论文

  • 发表日期：

    2025年2月14日

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  • Klaus Hackner,
  • Lisa Hütter,
  • Holger Flick,
  • Michael Grohs,
  • Kastriot Kastrati,
  • Hans Kiener,
  • David Lang,
  • Birgit Mosheimer-Feistritzer,
  • Helmut Prosch,
  • Eva Rath,
  • Otmar Schindler,
  • Florentine Moazedi-Fürst

摘要

Objective

Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a major driver of premature mortality in patients with rheumatoid arthritis (RA). Detection of RA-ILD is crucial but requires awareness among the treating physicians. To date, however, there is no international recommendation concerning screening for ILD in RA patients.

Methods

After a systematic literature review, the modified Delphi technique in combination with the nominal group technique was used to provide a Delphi consensus statement elaborated by an expert panel of pneumonologists, rheumatologists, and a radiologist. Based on the available evidence, several clusters of questions were defined and discussed until consent was reached.

Results

A screening algorithm for ILD in patients with RA based on clinical signs, respiratory symptoms, and risk factors has been developed. Further, the recommendations address diagnostic tools for RA-ILD and the follow-up of RA patients qualifying for ILD screening.