Bioassays zur Quantifizierung der „cystic fibrosis transmembrane conductance regulator“-Funktion

Bioassays for the quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) function play a crucial role in the diagnosis, treatment and monitoring of CF (cystic fibrosis) and CFTR-related diseases. They enable the identification of patients who can benefit from CFTR modulator treatment and aid in monitoring the efficacy of these treatments. The various available tests provide valuable insights into CFTR function in vivo and in vitro and enable personalized treatment approaches.