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<p>Filtration is a crucial element in most industrial processes, which has led to the development of numerous commercially available membrane-based filtration techniques. Membranes are notorious for fouling requiring frequent replacement and high maintenance costs. Here, we re-evaluate membrane-less filtration techniques as a versatile alternate approach to suit different particle sizes and filtration purposes. Industrial sectors favor highly scalable processes, which can explain the rapid development in this research space. As an alternative to membrane filtration, microfluidic techniques are among the most innovative methods and benefit from low-cost fabrication technology, continuous operational mode, and clogging-free separation methods. This review highlights microfluidic technologies with the potential for scale-up that could pivot away from our use of expensive conventional filtration methods.</p>

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Membrane-less microfiltration using microfluidics

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月28日

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  • Fateme Mirakhorli,
  • Zahra Lotfibakalani,
  • Lin Ding,
  • Hossein Ahmadi Nejad Joushani,
  • Jesus Shrestha,
  • Peter J. Ralph,
  • Majid Ebrahimi Warkiani

摘要

Filtration is a crucial element in most industrial processes, which has led to the development of numerous commercially available membrane-based filtration techniques. Membranes are notorious for fouling requiring frequent replacement and high maintenance costs. Here, we re-evaluate membrane-less filtration techniques as a versatile alternate approach to suit different particle sizes and filtration purposes. Industrial sectors favor highly scalable processes, which can explain the rapid development in this research space. As an alternative to membrane filtration, microfluidic techniques are among the most innovative methods and benefit from low-cost fabrication technology, continuous operational mode, and clogging-free separation methods. This review highlights microfluidic technologies with the potential for scale-up that could pivot away from our use of expensive conventional filtration methods.