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Purpose <p>To evaluate the role of ultrasound screening for fetal structural abnormalities at 20 and 30&#xa0;weeks’ gestation.</p> Methods <p>This retrospective study included women with singleton pregnancies who underwent routine ultrasound screening at our hospital between May 2014 and April 2021. Participants received two ultrasound screening examinations: at 20 and 30&#xa0;weeks’ gestation. We evaluated the frequency and details of fetal structural abnormalities identified during each examination.</p> Results <p>A total of 10,560 pregnant women underwent ultrasound screening at 20 and 30&#xa0;weeks’ gestation and delivered at our hospital. Structural abnormalities were observed in 142 (1.3%) women; of note, screening examinations at 20 and 30&#xa0;weeks detected 42.3% and 23.9% of cases, respectively. Routine point-of-care ultrasound examinations performed between 20 and 30&#xa0;weeks and beyond 30&#xa0;weeks detected 8.5% and 6.3% of cases, respectively, with 19.0% of cases identified after birth. Cleft lip and palate and ventricular septal defects (VSDs) were the most common abnormalities detected at the 20-week ultrasound screening. At the 30-week ultrasound screening, in addition to hydronephrosis, VSD, and vascular rings, which were also detected at the 20-week ultrasound screening, diaphragmatic hernia, ovarian cysts, achondroplasia, duodenal atresia, and meconium peritonitis, which could be apparent later in pregnancy, were detected.</p> Conclusions <p>The 20-week ultrasound screening revealed common fetal structural abnormalities, and the 30-week ultrasound screening detected fetal structural abnormalities that failed to be detected during the 20-week ultrasound screening and became apparent later in pregnancy. Adding a 30-week ultrasound screening provides enhanced diagnostic details in comparison to 20-week screening.</p>

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Detection of fetal structural abnormalities at 20 and 30 weeks: a retrospective study of prenatal ultrasound screening

  • 期刊论文

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  • 发表日期：

    2025年12月13日

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  • Yuki Kamihara,
  • Katsusuke Ozawa,
  • Kohei Ogawa,
  • Jin Muromoto,
  • Rika Sugibayashi,
  • Seiji Wada,
  • Haruhiko Sago

摘要

Purpose

To evaluate the role of ultrasound screening for fetal structural abnormalities at 20 and 30 weeks’ gestation.

Methods

This retrospective study included women with singleton pregnancies who underwent routine ultrasound screening at our hospital between May 2014 and April 2021. Participants received two ultrasound screening examinations: at 20 and 30 weeks’ gestation. We evaluated the frequency and details of fetal structural abnormalities identified during each examination.

Results

A total of 10,560 pregnant women underwent ultrasound screening at 20 and 30 weeks’ gestation and delivered at our hospital. Structural abnormalities were observed in 142 (1.3%) women; of note, screening examinations at 20 and 30 weeks detected 42.3% and 23.9% of cases, respectively. Routine point-of-care ultrasound examinations performed between 20 and 30 weeks and beyond 30 weeks detected 8.5% and 6.3% of cases, respectively, with 19.0% of cases identified after birth. Cleft lip and palate and ventricular septal defects (VSDs) were the most common abnormalities detected at the 20-week ultrasound screening. At the 30-week ultrasound screening, in addition to hydronephrosis, VSD, and vascular rings, which were also detected at the 20-week ultrasound screening, diaphragmatic hernia, ovarian cysts, achondroplasia, duodenal atresia, and meconium peritonitis, which could be apparent later in pregnancy, were detected.

Conclusions

The 20-week ultrasound screening revealed common fetal structural abnormalities, and the 30-week ultrasound screening detected fetal structural abnormalities that failed to be detected during the 20-week ultrasound screening and became apparent later in pregnancy. Adding a 30-week ultrasound screening provides enhanced diagnostic details in comparison to 20-week screening.