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<p>Domestic pigs and wild boar are well-established reservoirs for zoonotic hepatitis E virus (HEV) but whether it also occurs in other <i>Suidae</i>, including warthog, is unknown. Serum samples from 267 free-ranging warthogs collected in Kruger National Park and Mokala National Park, South Africa, were tested for anti-HEV antibodies and for HEV RNA. Overall, 22% (58/267) of samples were seropositive, with significantly higher seroprevalence in Mokala National Park (32%) than Kruger National Park (13%) (χ<sup>2</sup> = 13, <i>p</i> = 0.0003). No HEV RNA was detected. These findings provide the first serological evidence of HEV exposure in African warthogs.</p>

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Serological Evidence of Hepatitis E Virus Exposure in Free-Ranging Warthogs (Phacochoerus africanus) in South Africa

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年8月5日

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  • Sarah Sallie,
  • Tongai G. Maponga,
  • Angela Daly,
  • Peter Buss,
  • Michele Miller,
  • Wolfgang Preiser

摘要

Domestic pigs and wild boar are well-established reservoirs for zoonotic hepatitis E virus (HEV) but whether it also occurs in other Suidae, including warthog, is unknown. Serum samples from 267 free-ranging warthogs collected in Kruger National Park and Mokala National Park, South Africa, were tested for anti-HEV antibodies and for HEV RNA. Overall, 22% (58/267) of samples were seropositive, with significantly higher seroprevalence in Mokala National Park (32%) than Kruger National Park (13%) (χ2 = 13, p = 0.0003). No HEV RNA was detected. These findings provide the first serological evidence of HEV exposure in African warthogs.