Scholarlink

Aim <p>This systematic review and meta-analysis assessed the associations of health symptoms and conditions and their consequences with disability retirement among middle-aged workers.</p> Methods <p>Searches were conducted in PubMed, Web of Science, PsychInfo, and Scopus from their inception until February 2025. Observational longitudinal studies involving workers aged 40–64 years were included. Two reviewers independently assessed the methodological quality of the studies. A random-effects meta-analysis was performed, with heterogeneity and publication bias evaluated.</p> Results <p>From 13,899 reports, 68 reports from 34 longitudinal studies (<i>N</i> = 3,743,192 participants) were included. The meta-analysis found that health symptoms, including long sleep (≥ 8.5 h, hazard ratio [HR] 1.79, 95% CI 1.35–2.37), insomnia (HR 1.45, CI 1.29–1.64), and pain (HR 2.09, CI 1.40–3.11), health conditions, including mental health conditions (HR 2.19, CI 1.78–2.70), musculoskeletal disorders (HR 2.13, CI 1.25–3.64), diabetes (HR 1.55, CI 1.02–2.34), hypertension (HR 1.25, CI 1.05–1.50), cardiovascular disease (HR 1.98, CI 1.59–2.47), respiratory disease (HR 1.60, CI 1.12–2.29), and limiting long-standing illnesses (HR 4.81, CI 2.05–11.30), and health consequences, including impaired perceived work ability (HR 6.21, CI 2.93–13.15), suboptimal self-rated general health (HR 3.28, CI 2.36–4.56), and daily activity limitations&#xa0;(HR 6.29, CI 3.74–10.57) contribute to the increased risk of all-cause disability retirement. Interactions between different comorbidities were additive.</p> Conclusions <p>This meta-analysis highlights the significant impact of sleep problems, mental health conditions, various chronic diseases, and impaired work ability on the risk of disability retirement among middle-aged workers. Targeted interventions to promote sleep management and health conditions, particularly mental health, are crucial to mitigating the risk of disability retirement.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Associations of health symptoms and conditions with disability retirement in middle-aged workers: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月20日

查看全文
  • Rahman Shiri,
  • Joonas Poutanen,
  • Mikko Härmä,
  • Jenni Ervasti,
  • Eija Haukka

摘要

Aim

This systematic review and meta-analysis assessed the associations of health symptoms and conditions and their consequences with disability retirement among middle-aged workers.

Methods

Searches were conducted in PubMed, Web of Science, PsychInfo, and Scopus from their inception until February 2025. Observational longitudinal studies involving workers aged 40–64 years were included. Two reviewers independently assessed the methodological quality of the studies. A random-effects meta-analysis was performed, with heterogeneity and publication bias evaluated.

Results

From 13,899 reports, 68 reports from 34 longitudinal studies (N = 3,743,192 participants) were included. The meta-analysis found that health symptoms, including long sleep (≥ 8.5 h, hazard ratio [HR] 1.79, 95% CI 1.35–2.37), insomnia (HR 1.45, CI 1.29–1.64), and pain (HR 2.09, CI 1.40–3.11), health conditions, including mental health conditions (HR 2.19, CI 1.78–2.70), musculoskeletal disorders (HR 2.13, CI 1.25–3.64), diabetes (HR 1.55, CI 1.02–2.34), hypertension (HR 1.25, CI 1.05–1.50), cardiovascular disease (HR 1.98, CI 1.59–2.47), respiratory disease (HR 1.60, CI 1.12–2.29), and limiting long-standing illnesses (HR 4.81, CI 2.05–11.30), and health consequences, including impaired perceived work ability (HR 6.21, CI 2.93–13.15), suboptimal self-rated general health (HR 3.28, CI 2.36–4.56), and daily activity limitations (HR 6.29, CI 3.74–10.57) contribute to the increased risk of all-cause disability retirement. Interactions between different comorbidities were additive.

Conclusions

This meta-analysis highlights the significant impact of sleep problems, mental health conditions, various chronic diseases, and impaired work ability on the risk of disability retirement among middle-aged workers. Targeted interventions to promote sleep management and health conditions, particularly mental health, are crucial to mitigating the risk of disability retirement.