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Purpose <p>To prospectively evaluate bilateral visual function in Japanese patients implanted with nondiffractive extended depth-of-focus (EDoF) intraocular lenses (IOLs).</p> Study design <p>Multisite prospective observational study.</p> Patients and methods <p>This study included 48 eyes of 24 Japanese patients with cataracts (mean age: 68.7 ± 9.2&#xa0;years) who underwent bilateral implantation of nondiffractive EDoF IOLs CNAET0 (Clareon Vivity, Alcon), made of high-water-content hydrophobic acrylic material. Three months postoperatively, binocular uncorrected and distance-corrected visual acuities (BUCVA and BDCVA) were assessed at far, 66&#xa0;cm, and 40&#xa0;cm. Binocular photopic contrast sensitivity (CSV-1000), binocular defocus curves, spectacle independence, and photic phenomena (glare, halo, starburst, and waxy vision) were also assessed.</p> Results <p>The mean logMAR BUCVA/BDCVA was –0.11/–0.15 at far, 0.05/0.08 at 66&#xa0;cm, and 0.18/0.22 at 40&#xa0;cm. Binocular contrast sensitivity was within the normal range for individuals aged 60–69&#xa0;years across all spatial frequencies. The mean defocus curve demonstrated 0.1 logMAR or better between −2.0 and +1.0 D addition, with better performance of 0.0 logMAR or better between −1.5 and +0.5 D addition. All patients were spectacle-independent for distance and intermediate vision, whereas nine of the 24 patients (37.5%) required spectacles for near vision. None of the patients reported severe photic phenomena; 17 patients (70.8%) did not experience glare or starburst, and 20 patients (83.3%) did not report halo or waxy vision.</p> Conclusion <p>Bilateral implantation of nondiffractive EDoF IOLs provided good binocular functional vision from far to near, although some patients may require spectacles for near vision. The photic phenomenon was minimal.</p>

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Binocular visual function of Japanese eyes with nondiffractive extended depth-of-focus intraocular lenses made of high water-content hydrophobic acrylic material

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  • 发表日期：

    2025年11月4日

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  • Hisaharu Suzuki,
  • Yuka Ota,
  • Seiichiro Hata,
  • Keiichiro Minami,
  • Hiroko Bissen-Miyajima

摘要

Purpose

To prospectively evaluate bilateral visual function in Japanese patients implanted with nondiffractive extended depth-of-focus (EDoF) intraocular lenses (IOLs).

Study design

Multisite prospective observational study.

Patients and methods

This study included 48 eyes of 24 Japanese patients with cataracts (mean age: 68.7 ± 9.2 years) who underwent bilateral implantation of nondiffractive EDoF IOLs CNAET0 (Clareon Vivity, Alcon), made of high-water-content hydrophobic acrylic material. Three months postoperatively, binocular uncorrected and distance-corrected visual acuities (BUCVA and BDCVA) were assessed at far, 66 cm, and 40 cm. Binocular photopic contrast sensitivity (CSV-1000), binocular defocus curves, spectacle independence, and photic phenomena (glare, halo, starburst, and waxy vision) were also assessed.

Results

The mean logMAR BUCVA/BDCVA was –0.11/–0.15 at far, 0.05/0.08 at 66 cm, and 0.18/0.22 at 40 cm. Binocular contrast sensitivity was within the normal range for individuals aged 60–69 years across all spatial frequencies. The mean defocus curve demonstrated 0.1 logMAR or better between −2.0 and +1.0 D addition, with better performance of 0.0 logMAR or better between −1.5 and +0.5 D addition. All patients were spectacle-independent for distance and intermediate vision, whereas nine of the 24 patients (37.5%) required spectacles for near vision. None of the patients reported severe photic phenomena; 17 patients (70.8%) did not experience glare or starburst, and 20 patients (83.3%) did not report halo or waxy vision.

Conclusion

Bilateral implantation of nondiffractive EDoF IOLs provided good binocular functional vision from far to near, although some patients may require spectacles for near vision. The photic phenomenon was minimal.