Scholarlink

Purpose <p>To evaluate the frequency, timing, and characteristics of intraocular pressure (IOP) spikes following standalone Gonioscopy-Assisted Transluminal Trabeculotomy (GATT), and to assess their predictors and management strategies.</p> Study design <p>A retrospective observational study.</p> Methods <p>A total of 210 eyes that underwent 360° GATT between September 2021 and January 2024 at our tertiary eye hospital were included. Demographics, best-corrected visual-acuity (BCVA), IOP, antiglaucoma medications, complications and interventions were recorded. IOP spikes were defined as &gt;30 mmHg or &gt;10 mmHg above baseline within two months postoperatively and classified as hyperacute (0–3 days), acute (4–9 days), or subacute (10–60 days). Surgical success was defined as IOP: 5–21 mmHg with ≥20% reduction from baseline. Primary outcomes included spike characteristics, associated factors, and success rates.</p> Results <p>Seventy-one eyes (33.8%) developed IOP spikes, with a mean IOP of 33.9±6.5 mmHg and duration of 2.0 ± 2.6 days. Hyperacute spikes had more fibrinoid reaction (<i>p</i>=0.026) and higher total success (<i>p</i>=0.049); acute spikes had higher maximal preoperative IOP and longer hyphema duration (<i>p</i>=0.02, <i>p</i>=0.006, respectively); and subacute spikes had prolonged topical corticosteroid use, longer axial length, and prior vitrectomy (<i>p</i>=0.003, <i>p</i>=0.04, <i>p</i>=0.004, respectively). Total surgical success was 91.9%, with higher rates in the non-spike group (99.3% vs. 77.5%, <i>p</i>&lt;0.001). Fibrinoid reaction, prolonged topical corticosteroid use, and prior vitrectomy were associated with postoperative IOP spikes.</p> Conclusion <p>Postoperative IOP spikes are significantly correlated with surgical failure following GATT. Their timing might reflect differences in underlying mechanisms. Prompt management of complications associated with IOP spikes is essential to reduce failure.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Insights into intraocular pressure spikes following gonioscopy-assisted transluminal trabeculotomy (GATT): timing, predictors and clinical outcomes

  • 期刊论文

  • 发表日期：

    2025年9月3日

查看全文
  • Gizem Taskin,
  • Nese Alagoz,
  • Ihsan Cakir,
  • Cigdem Altan,
  • Gulsah Gumus Akgun,
  • Tekin Yasar

摘要

Purpose

To evaluate the frequency, timing, and characteristics of intraocular pressure (IOP) spikes following standalone Gonioscopy-Assisted Transluminal Trabeculotomy (GATT), and to assess their predictors and management strategies.

Study design

A retrospective observational study.

Methods

A total of 210 eyes that underwent 360° GATT between September 2021 and January 2024 at our tertiary eye hospital were included. Demographics, best-corrected visual-acuity (BCVA), IOP, antiglaucoma medications, complications and interventions were recorded. IOP spikes were defined as >30 mmHg or >10 mmHg above baseline within two months postoperatively and classified as hyperacute (0–3 days), acute (4–9 days), or subacute (10–60 days). Surgical success was defined as IOP: 5–21 mmHg with ≥20% reduction from baseline. Primary outcomes included spike characteristics, associated factors, and success rates.

Results

Seventy-one eyes (33.8%) developed IOP spikes, with a mean IOP of 33.9±6.5 mmHg and duration of 2.0 ± 2.6 days. Hyperacute spikes had more fibrinoid reaction (p=0.026) and higher total success (p=0.049); acute spikes had higher maximal preoperative IOP and longer hyphema duration (p=0.02, p=0.006, respectively); and subacute spikes had prolonged topical corticosteroid use, longer axial length, and prior vitrectomy (p=0.003, p=0.04, p=0.004, respectively). Total surgical success was 91.9%, with higher rates in the non-spike group (99.3% vs. 77.5%, p<0.001). Fibrinoid reaction, prolonged topical corticosteroid use, and prior vitrectomy were associated with postoperative IOP spikes.

Conclusion

Postoperative IOP spikes are significantly correlated with surgical failure following GATT. Their timing might reflect differences in underlying mechanisms. Prompt management of complications associated with IOP spikes is essential to reduce failure.