<p>The Indo-Pacific region, encompassing the Indian and Pacific Oceans, marks a significant shift from the Asia–Pacific focus to a broader, interconnected strategic zone. This shift reflects the rising complexity of global power dynamics, notably China’s challenge to US supremacy, and the region’s critical role in global maritime trade. The strategic landscape of the Indo-Pacific is characterized by a diverse array of key actors—including China, India, Japan, and the USA—each pursuing distinct strategies and visions. This has resulted in a volatile mix of cooperation and contention, further complicated by the region’s economic and strategic prominence. The ASEAN and IORA frameworks highlight the need for nuanced, multilateral approaches to the region’s challenges. The EU engagement, which evolved from a narrow Asia–Pacific focus to a broader strategy, underscores a key dilemma: despite the 2021 Strategy for Cooperation in the Indo-Pacific demonstrating an intent to wield both soft and hard power, internal EU divisions hinder a unified policy. Similarly, Türkiye’s “Asia Anew” initiative has been conceptually and practically inadequate, complicating its Indo-Pacific engagement. Despite strained EU-Türkiye relations, Türkiye’s pivot to a broader Asian strategy requires strategic recalibration. This analysis argues that despite challenges in Ankara-Brussels engagements, the EU has a strategic opportunity to help Türkiye refine its initiative through an Indo-Pacific approach, fostering regional integration. By leveraging collaborative projects and enhancing diplomatic engagement with Türkiye, the EU can address strategic and economic challenges in the region while potentially bridging its internal divergences with broader regional imperatives.</p>