Meningeomrisiko durch längere Gestagenanwendung

Several studies currently indicate an association between the use of certain progestins and the risk of undergoing meningioma surgery. The risk seems to be associated with the dose and duration of use. The absolute incidence for such an event is low; however, with the broad use of magnetic resonance imaging (MRI) asymptomatic meningioma is detected in about 1% of the images. It is a challenge for gynecologists to decide for these patients, if the use of a progestin could induce further growth of such a tumor. In such a situation collaboration with a neuro-oncologist is highly recommended. Enquiring about a meningioma diagnosis in the past should be part of the general medical history before prescribing hormone preparations containing progestins.