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<p>Borderline ovarian cancer and low-grade serous ovarian cancer (LGSOC) account for approximately 10–20% of all ovarian cancers. Even though the prognosis for LGSOC is considerably better than that for high-grade serous ovarian cancer (HGSOC), with a&#xa0;significantly longer overall survival, the diagnosis is often made in younger women who have not yet completed family planning. The same applies to borderline ovarian cancer. In both cases, the crucial question arises as to the options for fertility preservation. While in borderline cancer such a&#xa0;procedure that preserves the uterus and at least one ovary or parts of the ovary is possible in all stages, in LGSOC this option is limited to stages IA and IC1. In stages IC2 and IC3, the only option left is controlled ovarian stimulation and comedication with aromatase inhibitors to preserve an oocyte reserve.</p>

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Borderline-Ovarialkarzinom und low-grade-seröses Ovarialkarzinom bei Patientinnen mit Kinderwunsch

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月7日

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  • Ricardo E. Felberbaum,
  • Anke Brössner,
  • Maria-Rita Anwander,
  • Wolfgang Küpker

摘要

Borderline ovarian cancer and low-grade serous ovarian cancer (LGSOC) account for approximately 10–20% of all ovarian cancers. Even though the prognosis for LGSOC is considerably better than that for high-grade serous ovarian cancer (HGSOC), with a significantly longer overall survival, the diagnosis is often made in younger women who have not yet completed family planning. The same applies to borderline ovarian cancer. In both cases, the crucial question arises as to the options for fertility preservation. While in borderline cancer such a procedure that preserves the uterus and at least one ovary or parts of the ovary is possible in all stages, in LGSOC this option is limited to stages IA and IC1. In stages IC2 and IC3, the only option left is controlled ovarian stimulation and comedication with aromatase inhibitors to preserve an oocyte reserve.