Kontrazeption und dermatologische Erkrankungen
摘要
Most skin diseases have a hormonal genesis or endocrine trigger factors. Therefore, hormonal contraceptives offer indications for dermatologic treatments.
ObjectivesThe aim of this study was to summarize the effects of oral, vaginal, intrauterine as well as injectable and implantable contraceptives on hormonally adressable dermatoses.
Materials and methodsThis review was created on the basis of a literature search in Pubmed using the search terms contraception, skin disease, dermatology, hormonal therapy, seborrhea, acne and hirsutism.
ResultsCombined oral contraceptives and vaginal rings are the most important treatment pillars for the treatment of seborrhea, acne, hirsutism and androgenetic alopecia. Individualized hormonal contraception through the targeted use of gestagen partial effects and advantageous routes of application can minimize unwanted skin rashes. Estrogen-free therapeutics such as hormonal intrauterine devices, the progesterone-only pill or gestagen implants worsen most of the dermatological diseases presented here.
ConclusionsThrough more intensive research into known contraceptives with objective recording of dermatological (side) effects, further indication areas can be identified in the future.