<p>The aim of the current systematic review and meta-analysis is to assess the effect of platelet-rich fibrin (PRF) on soft tissue augmentation around dental implants. The randomized clinical trials (RCT) that utilized PRF in soft tissue augmentation around dental implants were selected from different databases. The following parameters were measured: keratinized mucosa width (KMW), soft tissue thickness (STT), and crestal bone loss (CBL). The primary outcome was STT, while secondary outcomes included KMW and CBL. The outcomes were measured at baseline, 3 months, and 6 months. Thirteen articles were identified, including 264 patients with ages ranging from 18 to 62 years old, among which 9 articles were included in the meta-analysis. After 3 months of follow-up, there were no differences between implants placed with PRF and implants placed with connective tissue graft (CTG) in the STT (Chi² = 0.46, <i>P</i> = 0.79; I² = 0%) and in the KMW (Chi² = 0.39, <i>P</i> = 0.68; I² = 0%). Moreover, after 6 months, the meta-analysis of STT (95% CI: 0.05 to 1.15; <i>P</i> = 0.03, I² = 82%) and KMW (95% CI: 0.25 to 1.04, <i>P</i> = 0.002, I² = 0%) showed significant improvement in the implant with PRF in comparison to implant only. However, CBL didn’t show a significant difference between both the implant combined PRF and the implant only group after 6 months (95% CI: − 0.69 to 0.20; <i>P</i> = 0.27). In conclusion, PRF enhances peri-implant soft tissue augmentation by showing a short-term improvement of the treatment outcomes however, its long-term clinical effect on peri-implant tissue stability remains uncertain.</p>