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A reduced order model formulation for left atrium flow: an atrial fibrillation case

  • Caterina Balzotti,
  • Pierfrancesco Siena,
  • Michele Girfoglio,
  • Giovanni Stabile,
  • Jorge Dueñas-Pamplona,
  • José Sierra-Pallares,
  • Ignacio Amat-Santos,
  • Gianluigi Rozza

摘要

A data-driven reduced order model (ROM) based on a proper orthogonal decomposition-radial basis function (POD-RBF) approach is adopted in this paper for the analysis of blood flow dynamics in a patient-specific case of atrial fibrillation (AF). The full order model (FOM) is represented by incompressible Navier–Stokes equations, discretized with a finite volume (FV) approach. Both the Newtonian and the Casson’s constitutive laws are employed. The aim is to build a computational tool able to efficiently and accurately reconstruct the patterns of relevant hemodynamics indices related to the stasis of the blood in a physical parametrization framework including the cardiac output in the Newtonian case and also the plasma viscosity and the hematocrit in the non-Newtonian one. Many FOM-ROM comparisons are shown to analyze the performance of our approach as regards errors and computational speed-up.