Background <p>Smoking is one of the main causes of preventable disease and premature death. While existing evidence syntheses the cost-effectiveness of smoking cessation interventions for hospitalized patients and high-risk groups such as pregnant women or children, the evidence on the cost-effectiveness of non-pharmacological interventions for the general population remains relatively underdeveloped.</p> Methods <p>A systematic literature review was performed using MEDLINE, EMBASE, Cochrane Library, and NHS Health Economic Evaluation Database along with grey literature, pre-prints, and HTA reports.</p> Results <p>A total of 9,541 abstracts were screened, with 23 studies meeting the eligibility criteria. These studies focused on four main intervention types (i) face-to-face counseling, (ii) digital/telephone counseling, (iii) reimbursement, and (iv) awareness building. The ICERs ranged from − 332,320 EUR/QALY to 156,310 EUR/QALY. Of the 39 ICERs reported, 30 (76.9%) demonstrated superior cost-effectiveness for smoking cessation interventions. Nine studies reported strong dominance, where the intervention not only gained QALYs but also saved costs. On average, 0.02 QALYs (SD = 0.02) were gained per person. When Life-Years Saved (LYS) were used as the effectiveness measure with a range from EUR 192/LYS to EUR 17,908/LYS. All ICERs werebelow the EUR 25,000/LYS willingness to pay threshold.</p> Conclusion <p>The evidence suggests that smoking cessation interventions are general cost-effective in Europe. Personal counseling appears crucial for digital interventions to demonstrate cost-effectiveness. Also, awareness building could serve as a cost-effective means of supporting existing cessation programs.</p>

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Breaking the habit: a systematic review of the cost-effectiveness of non-pharmacological and combined interventions for smoking cessation in Europe

  • Alexander Braun,
  • Walter Hyll,
  • Eva Krczal

摘要

Background

Smoking is one of the main causes of preventable disease and premature death. While existing evidence syntheses the cost-effectiveness of smoking cessation interventions for hospitalized patients and high-risk groups such as pregnant women or children, the evidence on the cost-effectiveness of non-pharmacological interventions for the general population remains relatively underdeveloped.

Methods

A systematic literature review was performed using MEDLINE, EMBASE, Cochrane Library, and NHS Health Economic Evaluation Database along with grey literature, pre-prints, and HTA reports.

Results

A total of 9,541 abstracts were screened, with 23 studies meeting the eligibility criteria. These studies focused on four main intervention types (i) face-to-face counseling, (ii) digital/telephone counseling, (iii) reimbursement, and (iv) awareness building. The ICERs ranged from − 332,320 EUR/QALY to 156,310 EUR/QALY. Of the 39 ICERs reported, 30 (76.9%) demonstrated superior cost-effectiveness for smoking cessation interventions. Nine studies reported strong dominance, where the intervention not only gained QALYs but also saved costs. On average, 0.02 QALYs (SD = 0.02) were gained per person. When Life-Years Saved (LYS) were used as the effectiveness measure with a range from EUR 192/LYS to EUR 17,908/LYS. All ICERs werebelow the EUR 25,000/LYS willingness to pay threshold.

Conclusion

The evidence suggests that smoking cessation interventions are general cost-effective in Europe. Personal counseling appears crucial for digital interventions to demonstrate cost-effectiveness. Also, awareness building could serve as a cost-effective means of supporting existing cessation programs.