<p>This pilot study evaluates the feasibility and efficacy of augmented reality navigation as an auxiliary tool for electrode implantation in sacral neuromodulation and sphenopalatine ganglion stimulation. A prospective single-center observational study was conducted involving four patients. AR navigation, utilizing the Microsoft HoloLens^® 2 and specialized software, was employed for preoperative planning and real-time guidance during needle placement. Intraoperative fluoroscopy was reserved for final electrode position verification. Technical accuracy was assessed by calculating the Fiducial Registration Error (FRE). The mean FRE was 3.5 ± 1.75 mm, deemed clinically acceptable. AR navigation facilitated successful electrode implantation in all cases, significantly reducing intraoperative fluoroscopy time to 0.1 ± 0.1 min and mean radiation dose to 0.7 ± 0.5 mSv—an order of magnitude lower than standard fluoroscopy-guided procedures. The technology provided continuous 3D visualization, enhancing spatial understanding and procedural accuracy. Augmented reality navigation presents a promising, low-radiation alternative for complex neuromodulation procedures. It enables precise real-time 3D guidance, potentially improving safety and efficacy. Further standardization and multi-center studies are warranted to validate its clinical adoption and integration.</p>