Scholarlink

<p>Early postoperative symptom aggravation is a clinically relevant yet underexplored phenomenon following anterior ulnar nerve transposition for cubital tunnel syndrome (CuTS). This study aimed to define its incidence, identify predictive factors, and establish a threshold-based risk stratification model.&#xa0;We retrospectively reviewed 127 patients undergoing anterior subcutaneous transposition of the ulnar nerve between 2020 and 2023. Early symptom aggravation was defined as a postoperative deterioration in at least one clinical (VAS or PRUNE) or electrophysiological (CMAP or SNCV) indicator at two weeks post-surgery. Multivariate logistic regression and ROC curve analyses were performed to determine independent predictors and optimal thresholds.&#xa0;Early symptom aggravation occurred in 26.8% of patients. Multivariate analysis identified symptom duration (OR = 1.150, <i>p</i> &lt; 0.001) as a significant independent predictor. McGowan grade III showed a moderate association (OR = 3.224, <i>p</i> = 0.087). ROC analysis revealed excellent discriminative ability for symptom duration (AUC = 0.890) with an optimal threshold of 24.00 months (sensitivity 82.4%, specificity 86.2%). Other variables, including electrophysiological measures and demographics, demonstrated limited predictive value.&#xa0;Symptom duration and preoperative McGowan grade are key risk factors for early symptom aggravation after CuTS surgery. A simple threshold-based model can aid in preoperative counseling and expectation management. These findings highlight the need for timely surgical intervention to minimize neural deterioration and improve short-term outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Early symptom aggravation following ulnar nerve transposition for cubital tunnel syndrome: incidence, predictive factors, and threshold-based risk stratification

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月19日

查看全文
  • Tianyou Hu,
  • Yujie Bian,
  • Tao Zhou,
  • Qiankun Wang,
  • Hongxiang Zhou

摘要

Early postoperative symptom aggravation is a clinically relevant yet underexplored phenomenon following anterior ulnar nerve transposition for cubital tunnel syndrome (CuTS). This study aimed to define its incidence, identify predictive factors, and establish a threshold-based risk stratification model. We retrospectively reviewed 127 patients undergoing anterior subcutaneous transposition of the ulnar nerve between 2020 and 2023. Early symptom aggravation was defined as a postoperative deterioration in at least one clinical (VAS or PRUNE) or electrophysiological (CMAP or SNCV) indicator at two weeks post-surgery. Multivariate logistic regression and ROC curve analyses were performed to determine independent predictors and optimal thresholds. Early symptom aggravation occurred in 26.8% of patients. Multivariate analysis identified symptom duration (OR = 1.150, p < 0.001) as a significant independent predictor. McGowan grade III showed a moderate association (OR = 3.224, p = 0.087). ROC analysis revealed excellent discriminative ability for symptom duration (AUC = 0.890) with an optimal threshold of 24.00 months (sensitivity 82.4%, specificity 86.2%). Other variables, including electrophysiological measures and demographics, demonstrated limited predictive value. Symptom duration and preoperative McGowan grade are key risk factors for early symptom aggravation after CuTS surgery. A simple threshold-based model can aid in preoperative counseling and expectation management. These findings highlight the need for timely surgical intervention to minimize neural deterioration and improve short-term outcomes.