<p>The gallbladder can be affected by various acute conditions beyond uncomplicated cholecystitis, with the prevalence of gallstones having risen over the past three decades. Management of biliary diseases is complex and necessitates careful case-by-case consideration. Radiologic imaging plays a crucial role in the evaluation, diagnosis, and management planning of biliary pathologies. This review explores acute gallbladder conditions such as simple cholecystitis, gangrenous cholecystitis, emphysematous cholecystitis, hemorrhagic cholecystitis, perforated cholecystitis, gallbladder fistulas, gallstone ileus, Bouveret syndrome, Mirizzi syndrome, gallbladder herniation, volvulus, trauma, pseudoaneurysm, portal venous thrombosis, and gallbladder carcinoma. It highlights the utility of various imaging modalities including ultrasound, CT, dual-energy CT, MRI, and MRCP in diagnosing these conditions. Advancements in imaging techniques have enhanced the ability to detect and characterize gallbladder diseases, facilitating timely surgical interventions and improving patient outcomes. This review emphasizes the importance of close collaboration between radiologists and clinicians to optimize diagnosis and management strategies, underscoring the indispensable role of radiologic imaging in modern medicine.</p> Graphical Abstract <p></p>