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<p>Surgical scars of the nasal region following basal cell carcinoma (BCC) excision often present aesthetic and functional challenges, particularly the “trap-door” deformity related to flap reconstruction. Fractional CO₂ laser represents a promising therapeutic option to improve scar quality through collagen remodeling and dermal reorganization. This retrospective study analysed eight patients (six males and two females, mean age 71 ± 10 years) with nasal post-surgical scars after BCC excision and flap reconstruction. All patients underwent two sessions of fractional CO₂ laser in Deep Pulse or High Pulse modes, with a two-month interval between treatments. Clinical outcomes were evaluated using the Patient and Observer Scar Assessment Scale (POSAS) and three-dimensional profilometry with the Antera 3D system before treatment and two months after the last session. A statistically significant improvement was observed in both patient-reported (overall opinion <i>p</i> = 0.0007; thickness <i>p</i> = 0.03) and observer-reported parameters (vascularity <i>p</i> = 0.007; thickness <i>p</i> = 0.005; pliability <i>p</i> = 0.02; overall opinion <i>p</i> = 0.00004). Antera 3D analysis showed a mean reduction in scar depression of 23.5% (<i>p</i> = 0.01). All patients developed transient erythema and edema that were resolved within a week. Fractional CO₂ laser proved to be a safe and effective method to improve nasal post-surgical scars, enhancing texture, vascularity, and contour.</p>

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Fractional CO2 laser treatment of post-surgical nasal scars: a retrospective analysis on 8 patients

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月2日

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  • Emanuele Maria Cipollini,
  • Luca Mariano,
  • Cristiano Morini,
  • Alessandro Clementi,
  • Luca Guarino,
  • Marco Gratteri,
  • Elena Zappia,
  • Annunziata Dattola,
  • Steven Paul Nisticò,
  • Giovanni Cannarozzo

摘要

Surgical scars of the nasal region following basal cell carcinoma (BCC) excision often present aesthetic and functional challenges, particularly the “trap-door” deformity related to flap reconstruction. Fractional CO₂ laser represents a promising therapeutic option to improve scar quality through collagen remodeling and dermal reorganization. This retrospective study analysed eight patients (six males and two females, mean age 71 ± 10 years) with nasal post-surgical scars after BCC excision and flap reconstruction. All patients underwent two sessions of fractional CO₂ laser in Deep Pulse or High Pulse modes, with a two-month interval between treatments. Clinical outcomes were evaluated using the Patient and Observer Scar Assessment Scale (POSAS) and three-dimensional profilometry with the Antera 3D system before treatment and two months after the last session. A statistically significant improvement was observed in both patient-reported (overall opinion p = 0.0007; thickness p = 0.03) and observer-reported parameters (vascularity p = 0.007; thickness p = 0.005; pliability p = 0.02; overall opinion p = 0.00004). Antera 3D analysis showed a mean reduction in scar depression of 23.5% (p = 0.01). All patients developed transient erythema and edema that were resolved within a week. Fractional CO₂ laser proved to be a safe and effective method to improve nasal post-surgical scars, enhancing texture, vascularity, and contour.