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<p>We report a rare case of hospital-acquired meningitis caused by pandrug-resistant <i>Chryseobacterium gleum</i>, which presumed susceptibility to linezolid (inhibition zone, 22&#xa0;mm). Treatment with ciprofloxacin and piperacillin-tazobactam failed, but adding linezolid led to recovery. This case suggests that linezolid may represent a potential adjunctive option for pandrug-resistant <i>C. gleum</i> meningitis.</p>

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Meningitis due to pandrug resistant Chryseobacterium gleum: microbiological cure and clinical response with linezolid-based combination therapy

  • 期刊论文

  • 发表日期：

    2026年1月3日

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  • Leilei Wang,
  • Yingmin Bi,
  • Yu Zhou,
  • Fan Yang

摘要

We report a rare case of hospital-acquired meningitis caused by pandrug-resistant Chryseobacterium gleum, which presumed susceptibility to linezolid (inhibition zone, 22 mm). Treatment with ciprofloxacin and piperacillin-tazobactam failed, but adding linezolid led to recovery. This case suggests that linezolid may represent a potential adjunctive option for pandrug-resistant C. gleum meningitis.