Purpose <p>Cutaneous botryomycosis is a chronic, granulomatous infection of the skin caused by different bacteria that form granular aggregates. We aim to provide a complete, comprehensive, and updated review of cutaneous botryomycosis, including a review of cases published in the last decade.</p> Results <p>Patients with botryomycosis typically present multiple nodules, sinuses, abscesses, fistulae, and ulcers, which develop during weeks or months. The current gold standard for diagnosing botryomycosis involves a combination of histopathological examination and microbial culture. A definitive diagnosis is established when clinical and pathological findings align with the presence of botryomycosis, supported by the identification of non-filamentous bacteria forming granules and positive culture. The most frequent isolated etiological agents are <i>Staphylococcus aureus</i> followed by <i>Pseudomonas aeruginosa</i>. The differential diagnosis includes mycetoma, actinomycosis, and carcinomas/sarcomas. Treatment includes antibiotics and, in selected cases, surgical debridement.</p>