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<p>This study evaluates the added value of using enrichment broths for improving the detection of multidrug-resistant (MDR) bacteria—VRE, ESBL producers, and carbapenemase-producing organisms (CPOs)—from rectal swabs. Comparing direct plating to enrichment-based methods significantly increased detection sensitivity, especially for CPOs (from 17 to 27 cases, a 58.8% increase). Detection rates for ESBL producers and VRE also improved significantly (by 20%). Pre-enrichment is therefore a valuable addition to routine MDR bacteria screening protocols, which is particularly useful when high accuracy is needed for prevention and infection control as well as for outbreak management.</p>

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Optimized detection of ESBL producers, carbapenemase producers, and VRE from rectal swabs using enrichment broth for superior screening sensitivity

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月26日

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  • Dominique S Blanc,
  • Massiha Kamyar,
  • Patrice Nordmann,
  • Laurent Poirel,
  • Gilbert Greub

摘要

This study evaluates the added value of using enrichment broths for improving the detection of multidrug-resistant (MDR) bacteria—VRE, ESBL producers, and carbapenemase-producing organisms (CPOs)—from rectal swabs. Comparing direct plating to enrichment-based methods significantly increased detection sensitivity, especially for CPOs (from 17 to 27 cases, a 58.8% increase). Detection rates for ESBL producers and VRE also improved significantly (by 20%). Pre-enrichment is therefore a valuable addition to routine MDR bacteria screening protocols, which is particularly useful when high accuracy is needed for prevention and infection control as well as for outbreak management.