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Purpose <p>The role of factors that could be associated with the diagnosis, hospitalisation, and severity risk of virus-caused acute respiratory infections (ARIs) is limited in Mexican children and adolescents.</p> Methods <p>To determine whether demographic and clinical factors may be associated with viral infections, a cross-sectional study was conducted at the Hospital Infantil de México “Federico Gómez” from January 2021 to December 2022. Nasopharyngeal swabs from patients with respiratory symptoms were tested for a PCR-based multiplexed nucleic acid test to identify respiratory pathogens, including SARS-CoV-2.</p> Results <p>Among the 2,133 positive viral tests, 71% were mono-infections, and 29% were co-infections, with Rhinovirus/Enterovirus being the most frequent virus in this population. Besides, a negative association was identified in co-infecting viruses. Several demographics (age and gender) and clinical factors (signs/symptoms, comorbidities [immunosuppression and cardiovascular disease], and immunisation status [Flu and COVID-19 vaccination]) were associated with virus aetiology, the nature of the infection and patient status.</p> Conclusions <p>Our data highlights the relevance of the factors related to virus-caused ARIs in paediatric patients. These factors could help clinicians manage medical cases regarding diagnosis, hospitalisation, and severity risk.</p> Clinical trial number <p>Not applicable.</p>

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Demographic and clinical factors are relevant in respiratory infections among paediatric patients: a cross-sectional study in Mexico

  • 期刊论文

  • 发表日期：

    2025年5月23日

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  • Alejandro Flores-Alanis,
  • Griselda Rodríguez-Martínez,
  • Zeus Saldaña-Ahuactzi,
  • Israel Parra-Ortega,
  • Ebzadrel Carbajal-Franco,
  • Marcela Salazar-García,
  • Fernando Ortega-Riosvelasco,
  • Víctor Olivar-López,
  • Yolanda P. Alemán-García,
  • Guillermina Campos-Valdez,
  • Jorge González-Gutiérrez,
  • Silvia Martínez-Valverde,
  • Victor M. Luna-Pineda

摘要

Purpose

The role of factors that could be associated with the diagnosis, hospitalisation, and severity risk of virus-caused acute respiratory infections (ARIs) is limited in Mexican children and adolescents.

Methods

To determine whether demographic and clinical factors may be associated with viral infections, a cross-sectional study was conducted at the Hospital Infantil de México “Federico Gómez” from January 2021 to December 2022. Nasopharyngeal swabs from patients with respiratory symptoms were tested for a PCR-based multiplexed nucleic acid test to identify respiratory pathogens, including SARS-CoV-2.

Results

Among the 2,133 positive viral tests, 71% were mono-infections, and 29% were co-infections, with Rhinovirus/Enterovirus being the most frequent virus in this population. Besides, a negative association was identified in co-infecting viruses. Several demographics (age and gender) and clinical factors (signs/symptoms, comorbidities [immunosuppression and cardiovascular disease], and immunisation status [Flu and COVID-19 vaccination]) were associated with virus aetiology, the nature of the infection and patient status.

Conclusions

Our data highlights the relevance of the factors related to virus-caused ARIs in paediatric patients. These factors could help clinicians manage medical cases regarding diagnosis, hospitalisation, and severity risk.

Clinical trial number

Not applicable.