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Hepatitis E virus prevalence among HIV-2 infected individuals in central Portugal

  • João Pereira-Vaz,
  • Anália Carmo,
  • Vítor Duque,
  • Cristina Luxo,
  • Ana Alves,
  • Alexandra Mendes,
  • Célia Morais,
  • Cláudio Gaspar,
  • Raquel Costa,
  • Lurdes Correia,
  • Fernando Rodrigues,
  • Ana Matos

摘要

To date, no studies comparing the prevalence of hepatitis E virus (HEV) infection between the general and human immunodeficiency virus 2 (HIV-2) populations are available. With the purpose of filling this gap, this prevalence was assessed in the HIV-2 population from central Portugal. HEV seropositivity was 19.4%, which did not differ significantly from that found in the matched control population, and was not associated with CD4 cell count, HIV-2 viral load, and geographic origin or travel history to regions considered highly endemic for HEV. The results suggest that HIV-2 is not a risk factor for HEV infection, neither for an increased occurrence of chronic HEV infection.