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The role of time to positive blood cultures in enhancing the predictive capability of DENOVA score for diagnosing infective endocarditis in patients with Enterococcus faecalis bacteremia

  • M Teresa Pérez-Rodríguez,
  • Olalla Lima,
  • Martín Garrido,
  • Anniris Rincón,
  • Lucía Martínez-Lamas,
  • Alexandre Pérez-González,
  • Alejandro Araújo,
  • Antía Amoedo,
  • Adrián Sousa,
  • Ana López,
  • Xurxo Cabrera,
  • Martín Rubianes

摘要

DENOVA-score is useful to stratify the risk of infective endocarditis (IE) in Enterococcus faecalis bacteremia. Recently, time to positive (TTP) of blood cultures has also been related with a higher risk of IE. The objective was to evaluate DENOVA- score with TTP to improve its specificity. We performed a retrospective, case–control study in adult patients with E. faecalis bacteremia. Thirty-nine patients with definite E. faecalis IE and 82 with E. faecalis bacteremia were included. The addition of a TTP ≤ 8 h to DENOVA-score did not improve the diagnostic accuracy of this score.