Scholarlink

Introduction <p>There is growing incidence of postpartum stroke globally. We aim to assess the incidence rate, predicting factors and outcome of postpartum stroke in a middle income country. In one year long bidirectional study, patients with acute postpartum stroke developed within six weeks after delivery were cases compared to matched control group without stroke in 1:2 ratio. Gestational age, number of pregnancies, BMI, comorbid conditions, evidence of infection, history of stroke, headache, proteinuria, and anemia at time of presentation were exposure variables. The outcome measures were incidence of postpartum stroke and functional outcome of postpartum stroke within four weeks of its development.</p> Results <p>The incidence rate was 112 new strokes per 100,000 deliveries. The mean ages of cases (290) and controls (400) were 29.5±7.4 and 26.6±5.2 respectively. Among postpartum strokes, 54.8% were ischemic, 22.4% hemorrhagic, 20% venous infarcts, and 2.8% RCVS. Compared with control group patient with postpartum stroke were more likely to be overweight (OR 2.6; 95%CI, 1.71-4.14), anemic (OR, 4.4; CI, 2.50, 8.06), grandmultiparous (OR 2.5 ; CI, 1.27, 5.15), smoker (3.4; CI, 1.76, 6.7), had history of previous stroke (3.77; CI, 1.84, 7.72), migraine (OR 15 ; CI, 8.58, 26.26), infection (OR 2.9; CI, 1.81, 4.94) and heavy proteinuria (OR 4.4; CI, 2.5, 8.06),. Among cases 32 (11%) were died while 70.9% of the survivors had no residual weakness. According to the modified Rankin Score, 79% of post-partum stroke patients had good outcomes, while 61 (21%) had poor outcomes, 32 of whom died within 28 days.</p> Conclusion <p>The incidence of postpartum stroke is increasing, particularly in low-income countries. Patients with established risk factors for postpartum stroke should get particular attention and all possible measures should be taken to mitigate those risk factors.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Incidence, predictors, types and outcome of Post-Partum stroke: A population based study

  • 期刊论文

  • 发表日期：

    2025年9月5日

查看全文
  • Javaria Aslam,
  • Shoaib Luqman,
  • Umair Arif,
  • Mazhar Faiz Alam,
  • Khursheed Muzammil,
  • Saima Nasreen,
  • Muhammad Danial Khan,
  • Ayesha Ali Khan,
  • Amit Kumar Thakur

摘要

Introduction

There is growing incidence of postpartum stroke globally. We aim to assess the incidence rate, predicting factors and outcome of postpartum stroke in a middle income country. In one year long bidirectional study, patients with acute postpartum stroke developed within six weeks after delivery were cases compared to matched control group without stroke in 1:2 ratio. Gestational age, number of pregnancies, BMI, comorbid conditions, evidence of infection, history of stroke, headache, proteinuria, and anemia at time of presentation were exposure variables. The outcome measures were incidence of postpartum stroke and functional outcome of postpartum stroke within four weeks of its development.

Results

The incidence rate was 112 new strokes per 100,000 deliveries. The mean ages of cases (290) and controls (400) were 29.5±7.4 and 26.6±5.2 respectively. Among postpartum strokes, 54.8% were ischemic, 22.4% hemorrhagic, 20% venous infarcts, and 2.8% RCVS. Compared with control group patient with postpartum stroke were more likely to be overweight (OR 2.6; 95%CI, 1.71-4.14), anemic (OR, 4.4; CI, 2.50, 8.06), grandmultiparous (OR 2.5 ; CI, 1.27, 5.15), smoker (3.4; CI, 1.76, 6.7), had history of previous stroke (3.77; CI, 1.84, 7.72), migraine (OR 15 ; CI, 8.58, 26.26), infection (OR 2.9; CI, 1.81, 4.94) and heavy proteinuria (OR 4.4; CI, 2.5, 8.06),. Among cases 32 (11%) were died while 70.9% of the survivors had no residual weakness. According to the modified Rankin Score, 79% of post-partum stroke patients had good outcomes, while 61 (21%) had poor outcomes, 32 of whom died within 28 days.

Conclusion

The incidence of postpartum stroke is increasing, particularly in low-income countries. Patients with established risk factors for postpartum stroke should get particular attention and all possible measures should be taken to mitigate those risk factors.