Innovative multidisciplinary tool for screening bowel and bladder symptoms in multiple sclerosis

期刊论文
发表日期：

2024年11月20日

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Giampaolo Brichetto,
Stefania Musco,
Margherita Monti Bragadin,
Erica Grange,
Gianfranco Lamberti,
Vincenzo Pedace,
Sara Rinaldi,
Giulia Anelli,
Simona Ascanelli,
Raffaele Balsamo,
Antonio Bertolotto,
Assunta Bianco,
Laura Brambilla,
Filippo Cecconi,
Raffaella Cerqua,
Giancarlo Coghe,
Antonella Conte,
Francesco Corea,
Antonio Cortese,
Stefano De Biase,
Marco Della Cava,
Angela Di Girolamo,
Ezio Falletto,
Lauredana Ercolani,
Franco Granella,
Rosa Iodice,
Carmela Leone,
Ignazio Montisci,
Roberta Motta,
Carolina Nicoletti,
Alessandra Oggero,
Laura Pelizzari,
Federica Petraglia,
Maria Grazia Piscaglia,
Elisabetta Pedrazzoli,
Simone Pletto,
Sarah Rasia,
Francesco Savoca,
Elisabetta Signoriello,
Francesco Torresan,
Ignazio Roberto Zarbo

摘要

Introduction

Bowel and bladder symptoms are frequent in people with Multiple Sclerosis (PwMS) and early diagnosis and treatment become crucial to improve their quality of life (QoL). The study aims to design a multidisciplinary questionnaire for screening bladder and bowel symptoms in PwMS.

Materials and methods

The Bowel and Bladder Symptoms Screening in Multiple Sclerosis (BBSS-MS) questionnaire for screening bowel and bladder symptoms was designed in Italian following a three-steps process. In the first step, a dedicated board of experts identified a pool of items, which will be analysed for content, clarity, and consistency during the second step. During the third step, the relevance of each item was evaluated through a two-round process following the Delphi method. For each round of the Delphi method, medians, the 25th and 75th percentiles, and the IQR of the score for each statement were calculated. Stata 16.1 software was used to conduct all analyses.

Results

The Board identified 22 items to include in the BBSS-MS, based on existing questionnaire and clinical expertise. After discussing about the comprehensibility and clarity of items, the first version of the BBSS-MS composed of 22 items was proposed. Following, a Panel of 44 experts scored the relevance of each question and all the questions reached the score to be included in the questionnaire. The final 21-item version of the BBSS-MS was proposed.

Discussion and conclusion

To our knowledge, the BBSS-MS represents the first self-reported hybrid questionnaire for screening bladder and bowel symptoms in an Italian MS population.