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Crossed-reflex in antiphospholipid chorea

  • Joan Miquel Fernández-Vidal,
  • Gonzalo Olmedo-Saura,
  • Luis Antonio Querol-Gutiérrez,
  • Jaime Kulisevsky,
  • Jesús Pérez-Pérez

摘要

Chorea is a hyperkinetic movement disorder associated with various underlyingconditions, including autoimmune diseases such as antiphospholipid syndrome (APS). APS can manifest with a wide range of neurological symptoms, including chorea. We present a case of a 77-year-old man with subacute generalized chorea secondary to primary APS. Notably, the patient exhibited a left patellar crossed-reflex, a phenomenon rarely documented in chorea cases, the pathophysiology of which has not yet been elucidated. In summary, this case challenges the traditional demographics of antiphospholipid syndrome (APS) by suggesting a potential link between APS and late-age patients. It emphasizes the importance of considering APS in late-onset chorea cases.