Objective <p>To quantify the burden of osteoarthritis (OA) and give an account of the most recent data on incidence, prevalence, and years lived with disability (YLDs) of OA for the North Africa and Middle East (NAME) region over time with a particular focus on changes from 1990 to 2021.</p> Method <p>In this epidemiological study, data from the Global Burden of Disease 2021 study were used. The prevalence, incidence, and YLDs of OA were obtained for both sexes in 21 countries of the NAME region. These estimates are reported in the form of all-age numbers and age-standardized rates, together with their 95% uncertainty intervals (UIs).</p> Result <p>The all-age numbers of incidence, prevalence, and YLDs in 2021 were about 2.7 million (95% UIs, 2.4 to 3.0), 30.5 million (27.1 to 33.7), and 1.0 million (0.5 to 2.1). From 1990 to 2021, the burden of OA was higher in females than in males, and the rates of prevalence and YLDs increased as age rose. However, the rate of incidence increased until the ages 60–64 and then decreased. Kuwait had the highest burden, whereas Afghanistan had the lowest burden. The highest burden among OA subgroups was related to knee OA, while hip OA had the least attributable burden. Overall, the burden of OA had a direct association with the sociodemographic index (SDI).</p> Conclusion <p>In summary, the prevalence, incidence, and YLD rates of osteoarthritis have shown an upward trend across most countries. The disease is positively associated with female sex, age, and SDI, implementing targeted medical prevention and treatment interventions in high-SDI countries.</p> <p><Table Float="No" ID="Taba"> <tgroup cols="2"> <colspec align="left" colname="c1" colnum="1" /> <colspec align="left" colname="c2" colnum="2" /> <tbody> <row> <entry align="left" nameend="c2" namest="c1"> <p><b>Key Points</b></p> <p>• <i>This study presents a comprehensive analysis of the burden of osteoarthritis in North Africa and the Middle East from 1990 to 2021 using data from the Global Burden of Disease 2021 study. The findings highlight regional trends in osteoarthritis incidence, prevalence, and years lived with disability, offering valuable insights into healthcare planning and policy development.</i></p> </entry> </row> </tbody> </tgroup> </Table></p>

Burden of osteoarthritis in North Africa and Middle East from 1990 to 2021: findings from the Global Burden of Disease 2021 study

期刊论文
发表日期：

2025年11月27日

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Azin Rashidi,
Mohammad-Mahdi Bastan,
Ali Golestani,
Sina Azadnajafabad,
Nazila Rezaei,
Mohammadjavad Zeinodinimeymand,
Mohamed Busehail,
Masooma Yaqoob,
Mahsa Heidari-Foroozan,
Mohammad-Mahdi Rashidi

摘要

Objective

To quantify the burden of osteoarthritis (OA) and give an account of the most recent data on incidence, prevalence, and years lived with disability (YLDs) of OA for the North Africa and Middle East (NAME) region over time with a particular focus on changes from 1990 to 2021.

Method

In this epidemiological study, data from the Global Burden of Disease 2021 study were used. The prevalence, incidence, and YLDs of OA were obtained for both sexes in 21 countries of the NAME region. These estimates are reported in the form of all-age numbers and age-standardized rates, together with their 95% uncertainty intervals (UIs).

Result

The all-age numbers of incidence, prevalence, and YLDs in 2021 were about 2.7 million (95% UIs, 2.4 to 3.0), 30.5 million (27.1 to 33.7), and 1.0 million (0.5 to 2.1). From 1990 to 2021, the burden of OA was higher in females than in males, and the rates of prevalence and YLDs increased as age rose. However, the rate of incidence increased until the ages 60–64 and then decreased. Kuwait had the highest burden, whereas Afghanistan had the lowest burden. The highest burden among OA subgroups was related to knee OA, while hip OA had the least attributable burden. Overall, the burden of OA had a direct association with the sociodemographic index (SDI).

Conclusion

In summary, the prevalence, incidence, and YLD rates of osteoarthritis have shown an upward trend across most countries. The disease is positively associated with female sex, age, and SDI, implementing targeted medical prevention and treatment interventions in high-SDI countries.

Key Points

• This study presents a comprehensive analysis of the burden of osteoarthritis in North Africa and the Middle East from 1990 to 2021 using data from the Global Burden of Disease 2021 study. The findings highlight regional trends in osteoarthritis incidence, prevalence, and years lived with disability, offering valuable insights into healthcare planning and policy development.