Scholarlink

<p>Primary hypertrophic osteoarthropathy (PHO) is a rare systemic disorder characterized. by periosteal new bone formation, clubbing of fingers and toes, and thickening of the. skin, particularly on the forehead and face. This case study presents a 24-year-old. male patient with a decade-long history of prominent skin folds on the forehead and. face, joint swelling in hands and feet, and calf pain. Clinical manifestations included. progressive facial wrinkling, thickening of distal joints, and cortical thickening observed. on X-rays. Serum levels of insulin-like growth factor (IGF-1), thyroid function, rheumatoid factor, and anti-cyclic citrullinated peptide were within normal ranges. The diagnosis was confirmed through a comprehensive evaluation of clinical, radiological, and laboratory findings. This report underscores the importance of recognizing the. distinct features of PHO for accurate diagnosis and timely management.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

History of primary hypertrophic osteoarthropathy

  • 期刊论文

  • 发表日期：

    2025年3月28日

查看全文
  • Ruiyao Hu,
  • Xinbo Yu,
  • Zhimin Lin,
  • Shufeng Wei,
  • Naigang Chen,
  • Yiwei Guan,
  • Chen Li

摘要

Primary hypertrophic osteoarthropathy (PHO) is a rare systemic disorder characterized. by periosteal new bone formation, clubbing of fingers and toes, and thickening of the. skin, particularly on the forehead and face. This case study presents a 24-year-old. male patient with a decade-long history of prominent skin folds on the forehead and. face, joint swelling in hands and feet, and calf pain. Clinical manifestations included. progressive facial wrinkling, thickening of distal joints, and cortical thickening observed. on X-rays. Serum levels of insulin-like growth factor (IGF-1), thyroid function, rheumatoid factor, and anti-cyclic citrullinated peptide were within normal ranges. The diagnosis was confirmed through a comprehensive evaluation of clinical, radiological, and laboratory findings. This report underscores the importance of recognizing the. distinct features of PHO for accurate diagnosis and timely management.