<p>Laboratory experiments have revealed that the friction coefficient within landslide shear bands exhibits rate dependence, which is the key factor in explaining the mechanism of high-speed and long-runout movement. However, the rate-dependent effect is overlooked due to the constant frictional value in the conventional Coulomb Friction (CF) law. To address this limitation, we propose using the relative shear rate between particles as an indicator, and integrating the Rate-dependent Friction (RF) law with the discrete element method to investigate the effects of interparticle friction coefficient (<i>µ</i>_micro) weakening on the dynamics of the “10.10” Baige landslide. We compared the impact of the CF law, one-state RF law, and two-state RF law on landslide dynamics under the same friction parameters. The results suggest that the weakening of <i>µ</i>_micro leads to a maximum increase of the sliding rate and displacement by 37.0% and 19.7%. Surprisingly, the two-state RF law exhibits the most robust coupling with the evolution stages of the landslide, which can be divided into initial creep, particle flow, and accumulation phases. Furthermore, the relationship between the apparent friction coefficient (<i>µ</i>_macro) and <i>µ</i>_micro was revealed as positively logarithmic, indicating that the weakening of <i>µ</i>_micro enhances the fluidity of the landslide. These findings are expected to improve the accuracy of landslide dynamic simulations further.</p>