<p>Landslide hazards are common problems in the rift escarpments and highlands of Ethiopia, causing damage to infrastructures, agricultural lands, and human lives. The Gedo-Dilb asphalt road, which crosses the western rift escarpments of northern Ethiopia, is frequently affected by landslides. The study aims to analyze spatial distributions of landslides and generate a landslide susceptibility map (LSM). The research work involved: (a) detailed inventory and characterization of landslides, and (b) evaluation of the landslides and their associations with different causative factors. Landslide inventory of the area was produced using Google Earth imagery, aerial photos, and intensive field campaigns. Accordingly, a total of 103 landslides were inventoried, encompassing an area of 8.44 km². The main landslide types found in the area are rockfalls, debris/earth flows, and debris/earth slides. Seven causative factors were identified and used for landslide susceptibility mapping, namely: distance to stream, slope gradient, distance to road, land use land cover, lithology, plan and profile curvatures. Analytical hierarchy process (AHP) approach was used, and the model was validated using the area under the receiver operating characteristic (ROC) curve. The area under the curve (AUC) value was found to be 0.8198, indicating very good prediction of landslide susceptibility in the study area. It was observed that 75.12% of the inventoried landslides fall in the high and very high susceptibility zones. The AHP weight result revealed that slope gradient, lithology, and distance to stream played a major role in landslide occurrences. The resulting map would be important for regional spatial planning and future infrastructure development.</p>