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<p>The market for small-diameter vascular grafts (&lt; 6&#xa0;mm) used in cardiac and vascular surgery has not yet been fully established, as stable long-term patency has not been achieved. This paper focuses on the clinical development of tissue-engineered vascular grafts (TEVGs), especially those that have progressed to clinical trials, and introduces their current status with historical background and future directions. This review was created based on a translation of the Japanese review first reported in the <i>Japanese Journal of Artificial Organs</i> in 2023 (vol. 52, no. 3, pp. 161–166), with some modifications. </p>

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Artificial blood vessels-clinical development of TEVG

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月26日

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  • Manabu Itoh,
  • Keiji Kamohara,
  • Koichi Node,
  • Koichi Nakayama

摘要

The market for small-diameter vascular grafts (< 6 mm) used in cardiac and vascular surgery has not yet been fully established, as stable long-term patency has not been achieved. This paper focuses on the clinical development of tissue-engineered vascular grafts (TEVGs), especially those that have progressed to clinical trials, and introduces their current status with historical background and future directions. This review was created based on a translation of the Japanese review first reported in the Japanese Journal of Artificial Organs in 2023 (vol. 52, no. 3, pp. 161–166), with some modifications.