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Recent advances in liquid biopsy of central nervous system lymphomas: case presentations and review of the literature

  • Manabu Natsumeda,
  • Satoshi Shibuma,
  • Haruhiko Takahashi,
  • Jotaro On,
  • Yoshihiro Mouri,
  • Kaoru Tomikawa,
  • Hidemoto Fujiwara,
  • Jun Watanabe,
  • Yoshihiro Tsukamoto,
  • Masayasu Okada,
  • Rui Takeda,
  • Hiroshi Shimizu,
  • Jun Takizawa,
  • Akiyoshi Kakita,
  • Makoto Oishi

摘要

Surgical biopsy is the gold standard for diagnosing central nervous system (CNS) lymphomas. However, reliable liquid biopsy methods for diagnosing CNS lymphomas have quickly developed and have been implicated in clinical decision-making. In the current report, we introduce two patients for whom liquid biopsy was essential for diagnosing CNS lymphomas and discuss the rapidly growing applications of this technology.