Scholarlink

<p>A copper-coordinated poly-L-histidine/carboxylated multi-walled carbon nanotube (Cu-HIS/<i>f</i>-MWCNTs) sensing interface was constructed using electropolymerization and self-assembly methods. The electrochemical response of shikonin (SHI) on this sensing interface was analyzed using cyclic voltammetry (CV) and chronoamperometry (CC). The results showed that the interface had a large effective surface area, and the imidazole groups on histidine exhibited good recognition and electrocatalytic oxidation of shikonin. At optimal conditions, the differential pulse voltammetry (DPV) peak current demonstrated a linear dependence on shikonin concentration within the range of 2 × 10<sup>−4</sup> to 10&#xa0;µmol/L, achieving a detection limit of 0.07&#xa0;nmol/L. The sensing interface demonstrated a broad detection range, along with excellent stability, selectivity, and reproducibility. It was successfully employed for the analysis of shikonin in real samples, yielding a spiked recovery rate from 98.4 to 104.8%.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Electrochemical sensing interface of copper-coordinated polyhistidine/functionalized multi-walled carbon nanotubes for shikonin determination

  • 期刊论文

  • 发表日期：

    2025年2月27日

查看全文
  • Rong Wang,
  • Liangqin Zhu,
  • Jianfei Wang,
  • Chenglong Zeng,
  • Ying Chen,
  • Yan Wei

摘要

A copper-coordinated poly-L-histidine/carboxylated multi-walled carbon nanotube (Cu-HIS/f-MWCNTs) sensing interface was constructed using electropolymerization and self-assembly methods. The electrochemical response of shikonin (SHI) on this sensing interface was analyzed using cyclic voltammetry (CV) and chronoamperometry (CC). The results showed that the interface had a large effective surface area, and the imidazole groups on histidine exhibited good recognition and electrocatalytic oxidation of shikonin. At optimal conditions, the differential pulse voltammetry (DPV) peak current demonstrated a linear dependence on shikonin concentration within the range of 2 × 10−4 to 10 µmol/L, achieving a detection limit of 0.07 nmol/L. The sensing interface demonstrated a broad detection range, along with excellent stability, selectivity, and reproducibility. It was successfully employed for the analysis of shikonin in real samples, yielding a spiked recovery rate from 98.4 to 104.8%.